Bio-pigments are the colored primary and secondary metabolites released by microbes under stress conditions and are crucial for adaptation.Bio-pigments are being widely accepted for industrial utilization due to their natural form, organic source, and biodegradability.Also, the ease of cultivation, Top scalability and cost-effectiveness in terms of
Role of PLK1/NUMB/NOTCH in epithelial-mesenchymal transition in human melanoma
Abstract Polo-like kinase 1 (PLK1), a serine/threonine kinase, is overexpressed in melanoma and its expression has been associated with poor disease prognosis.PLK1 has been shown to interact with NUMB, a NOTCH antagonist.However, the exact role of PLK1, NUMB, and NOTCH signaling in epithelial-mesenchymal transition (EMT) in melanoma progression is
Study of Theory Based on Security at Silimo Settlement in The Baliem Valley of Papua
In the Baliem Valley, Papua, the tradition of tribal wars in the culture of the Hubula tribe in the past is related to the concept of siteselection, spatial planning,and building form in the Silimo settlement.The problem in this study is how the selection of location, spatial planning, building form, and territoriality becomethe concept of security
Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I.
Ribosome Horse Grooming Combs biogenesis is essential for cell growth and proliferation and is commonly elevated in cancer.Accordingly, numerous oncogene and tumor suppressor signaling pathways target rRNA synthesis.In breast cancer, non-canonical Wnt signaling by Wnt5a has been reported to antagonize tumor growth.Here, we show that Wnt5a rapidly r
A Buck-Boost Converter; Design, Analysis and Implementation Suggested for Renewable Energy Systems
This work introduces a new non-isolated buck-boost DC-DC converter.Interleaved configuration of the suggested structure increases the voltage conversion ratio.The Handbag voltage rate of the suggested converter can be stepped-up and stepped down for lower values of duty-cycle, which causes to decrease in the conduction losses of the system.The volt